Weekly Roundup for SEPTEMBER 6, 2019: Recent Publications in Women’s Mental Health

By | September 10, 2019

Amygdala and affective responses to infant pictures; comparing depressed and non-depressed mothers and non-mothers.

Dudin A, Wonch KE, Davis AD, Steiner M, Fleming AS, Hall GB.  J Neuroendocrinol. 2019 Sep 5:e12790.

Women with PPD show an enhanced amygdala response to affectively positive infant pictures, but not to affectively positive pictures of scenery. Women with depression outside of the postpartum period show no change in amygdala responsiveness to either stimulus categories. 

Maternal perinatal mental health: Associations with bonding, mindfulness, and self-criticism at 18 months’ postpartum.

Brassel A, Townsend ML, Pickard JA, Grenyer BFS.  Infant Ment Health J. 2019 Sep 5.

Maternal depression and self-criticism significantly increased from pregnancy to postpartum. Maternal anxiety, self-criticism, and facets of mindfulness during pregnancy were also associated with mother-infant bonding at 18 months. 

Four maternal characteristics determine the 12-month course of chronic severe postpartum depressive symptoms.

Fisher SD, Sit DK, Yang A, Ciolino JD, Gollan JK, Wisner KL.  Depress Anxiety. 2019 Apr;36(4):375-383. 

Analyses resulted in identification of three distinct trajectories of depressive symptoms: (1) gradual remission (50.4%), (2) partial improvement (41.8%), and (3) chronic severe (7.8%). Key predictive characteristics of the chronic severe versus gradual remission and partial improvement trajectories included parity, education, and baseline global functioning and depression severity. 

Poor Postpartum Sleep Quality Predicts Subsequent Postpartum Depressive Symptoms in a High-Risk Sample.

McEvoy KM, Rayapati D, Washington Cole KO, Erdly C, Payne JL, Osborne LM.  J Clin Sleep Med. 2019 Aug 12.

Poor sleep quality in the early postpartum period independently predicts development of later PPD.

Brexanolone (Zulresso): Finally, an FDA-Approved Treatment for Postpartum Depression.

Powell JG, Garland S, Preston K, Piszczatoski C.  Ann Pharmacother. 2019 Sep 3.

Interpersonal trauma and suicide attempts in low-income depressed mothers in home visiting.

Ammerman RT, Scheiber FA, Peugh JL, Messer EP, Van Ginkel JB, Putnam FW.  Child Abuse Negl. 2019 Aug 29;97:104126.

History of suicide attempts is associated with childhood trauma history and later psychosocial impairments in low income, depressed mothers in home visiting.

Treatment resistant depression in women with peripartum depression.

Cepeda MS, Kern DM, Nicholson S.  BMC Pregnancy Childbirth. 2019 Sep 2;19(1):323. doi: 10.1186/s12884-019-2462-9.Free Article

TRD occurs in approximately 5% of women with peripartum depression. The risk of TRD is higher in pregnant women with a history of depression. Women who went on to develop TRD had more psychiatric comorbidities and painful conditions than women who did not.

Evaluation of a Technology-Based Peer-Support Intervention Program for Preventing Postnatal Depression (Part 1): Randomized Controlled Trial.

Shorey S, Chee CYI, Ng ED, Lau Y, Dennis CL, Chan YH.  J Med Internet Res. 2019 Aug 29;21(8):e12410. Free Article

In this randomized controlled trial, women received a 4-week-long intervention including weekly follow-up with a peer volunteer through phone calls or text messages. The intervention group received peer support in addition to the standard care offered by the hospital. The control group only received standard postpartum care. The technology-based intervention was found to be effective in reducing the risk of postpartum depression among new mothers and showed a generally positive trend in reducing postpartum anxiety and loneliness and increasing perceived social support. 

MGH Center for Women's Mental Health