Apr 11, - The advantages of diazepam in comparison to certain other benzodiazepines are a rapid onset of action and high efficacy rates, which are Missing: graphs. Apr 28, - Table 1. Benzodiazepine Equivalency Approximately Equivalent Oral Doses, mg Time to Peak Level, hours Half-life, hours Alprazolam (Xanax). The behavioral effects of each test drug (diazepam or zolpidem) were examined in In bar graphs, total ambulatory distances are expressed as means. of zolpidem in these mice, seizure onset latencies were defined as the time (in sec).
Diazepam onset and duration graphs- -
These processes are summarized in the Table. Following an intravenous bolus, drug introduced into the bloodstream central compartment distributes into peripheral tissues peripheral compartment. The first of these is that a drug may be considered completely eliminated following 4 half-lives and, secondly, steady state drug concentrations can be achieved following 4 half-lives provided the drug is administered at a consistent dose and schedule. Also, when considering drug elimination, attention must be given to any active metabolites of the parent drug. Received Jul 9; Accepted Sep 5.